VYPR
Unrated severityNVD Advisory· Published Mar 18, 2026· Updated Mar 19, 2026

NULL pointer dereference in samtools cram-size

CVE-2026-31973

Description

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the cram_decode_compression_header() was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

AI Insight

LLM-synthesized narrative grounded in this CVE's description and references.

Affected products

2
  • Samtools/SAMtoolsllm-create2 versions
    >=1.17+ 1 more
    • (no CPE)range: >=1.17
    • (no CPE)range: >= 1.17, < 1.21.1

Patches

Vulnerability mechanics

References

2

News mentions

0

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