VYPR
Unrated severityNVD Advisory· Published Mar 18, 2026· Updated Mar 19, 2026

NULL pointer dereference in samtools cram-size

CVE-2026-31973

Description

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the cram_decode_compression_header() was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Affected products

2
  • Samtools/SAMtoolsllm-create
    Range: >=1.17
  • samtools/samtoolsv5
    Range: >= 1.17, < 1.21.1

Patches

0

No patches discovered yet.

Vulnerability mechanics

AI mechanics synthesis has not run for this CVE yet.

References

2

News mentions

0

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